Here is more evidence that the danger of fat depends on where it’s located on your body. And the fat that we worry about for our looks is the harmless kind. This is further explanation of why body types that appear thin or within weight guidelines but are internally fat can have hidden risks.

Fat can be harmful or largely benign, depending on where in the body it is located. ‘Subcutaneous’ fat sits underneath the skin to store energy, and is generally harmless. Meanwhile, accumulation of ‘visceral’ fat, located in the abdomen, including around the liver, stomach and intestines, promotes inflammation and metabolic disturbances, and is associated with health complications such as type 2 diabetes and heart disease.

“It has been unclear why fat cells, which appear so similar, are associated with such different health outcomes,” says author Professor Katherine Samaras, Head of the Clinical Obesity, Nutrition and Adipose Biology lab at Garvan and endocrinologist at St Vincent’s Hospital Sydney. “Now we start to understand that the different fat cells are wired differently right from the start.”

Genomic “Map” Reveals Not All Fat Is Equal | Science Magazine